Epidermolysis Bullosa Acquired- Symptoms, Causes, Treatment and Home Remedies

What is Epidermolysis Bullosa Acquired?

Epidermolysis Bullosa Acquired(EBA) is an autoimmune disease. EBA is occurs in adulthood. Epidermolysis Bullosa Acquired is affected due to the genetic inheritance. It is skin disease. The male to female ratio is 1:1.4. This disease occur in any age. Epidermolysis Bullosa Acquired is very rare disease. The female patient had cyst of milia. Dire ct immunofluorescence shows IgG deposited at the dermo epidermal junction. EB can be acquired as well as inherited. It is usually associated with scarring and has blistering below the basement membrane zone.

Causes of Epidermolysis Bullosa Acquired

• Epidermolysis bullosa can be inherited
• This disease caused by T-cell infiltration in the small intestine.
• Infection of open wounds and sores
• Epidermolysis Bullosa Acquired is caused autosomal dominant disorder.

What are the symptoms of Epidermolysis Bullosa Acquired?

• It appears on the palms, soles.
• Patient cause excessive sweating.
• Blisters are seen on the hands, feet and extremities.
• The nails are thickened and sometimes absent.
• Patient causes diseases like Crohn disease, systemic lupus erythematosus, amyloidosis, multiple myeloma.

Epidermolysis Bullosa Acquired Treatment

• Preventing trauma and friction, and controlling secondary infections.
• Skin biopsy for direct and indirect immunoelectron microscopy.
• Epidermolysis Bullosa Acquired is treated with high dose frusemide.
• Epidermolysis Bullosa Acquired is treated with petroleum jelly, gauze, and ointments.
• Plastic surgery is also used to relief the mitten like deformities and to restore function of the fingers and toes.
• Protein therapy may used to replace a missing protein, it is best for skin structure.
• On long term systemic corticosteroid treatment with daily calcium and vitamin D supplements are useful for reducing steroid induced osteoporosis.
• Diet- hard or brittle foods and foods with high acid content should be avoided.
• Drug- Azathioprine adjust dose based on blood level of thiopurine methyltransferase.